Publications Magnesium disorders 6 Jun 20249 Jul 2024 Touyz RM, de Baaij JHF, Hoenderop JGJ N Engl J Med. 2024 Jun 6;390(21):1998-2009. Abstract Although the past several years have seen substantial advances in the understanding of molecular and cellular…
News Rosanna Gusmano ERA Award for Young Investigators in basic science for Jeroen de Baaij 23 May 20249 Jul 2024 Jeroen de Baaij has been awarded the Rosanna Gusmano Young Investigator Award for Basic Science of the European Renal Association (ERA). He receives this prestigious award for his work on the discovery of genetic causes…
News Reducing side effects of proton pump inhibitors 26 Apr 20249 Jul 2024 The Radboudumc Academic Medical Network invests in regional collaboration in the areas of prostate cancer, side effects of proton pump inhibitors, vaccines for individuals with compromised immune systems, and treatment…
News Kolff+ grant for more insight into cardiovascular disease in kidney patients 8 Apr 20249 Jul 2024 The leading cause of death in people with kidney damage is cardiovascular disease. This is probably due to accumulating calcium phosphate crystals in the blood. With a Kolff+ grant from…
Publications Liver and spleen predominantly mediate calciprotein particle clearance in a rat model of chronic kidney disease 3 Apr 20249 Jul 2024 Zeper LW, Bos C, Leermakers PA, Franssen GM, Raavé R, Hoenderop JGJ, de Baaij JHF Am J Physiol Renal Physiol. 2024 Apr 1;326(4):F622-F634 Abstract Calciprotein particles (CPPs) provide an efficient mineral…
Publications Hypomagnesaemia with varying degrees of extrarenal symptoms as a consequence of heterozygous CNNM2 variants 22 Mar 20249 Jul 2024 Bosman W, Franken GAC, de Las Heras J, Madariaga L, Barakat TS, Oostenbrink R, van Slegtenhorst M, Perdomo-Ramírez A, Claverie-Martín F, van Eerde AM, Vargas-Poussou R, Dubourg LD, González-Recio I,…
Publications Magnesium Supplementation Modulates T-cell Function in People with Type 2 Diabetes and Low Serum Magnesium Levels 27 Feb 20249 Jul 2024 Drenthen LCA, Ajie M, de Baaij JHF, Tack CJ, de Galan BE, Stienstra R. J Clin Endocrinol Metab. 2024 Feb 27:dgae097 Abstract Context: Low magnesium levels, which are common in people with…
News PhD Degree for Barnabas Ilenwabor 16 Feb 20249 Jul 2024 Barnabas Ilenwabor successfully defended his thesis entitled ‘Exploring novel regulatory pathways in renal magnesium homeostasis'. Outline of this thesisThe aim of this thesis is to provide further identify and characterize the…
Publications Mitochondrial Dysfunction in Kidney Tubulopathies 12 Feb 20249 Jul 2024 Hoogstraten CA, Hoenderop JG, de Baaij JHF Annu Rev Physiol. 2024 Feb 12;86:379-403 Abstract Mitochondria play a key role in kidney physiology and pathology. They produce ATP to fuel energy-demanding water…
Publications Genome-wide association study of serum magnesium in type 2 diabetes 22 Jan 20249 Jul 2024 Oost LJ, Slieker RC, Blom MT, 't Hart LM, Hoenderop JGJ, Beulens JWJ, de Baaij JHF. Genes Nutr. 2024 Jan 26;19(1):2. Abstract People with type 2 diabetes have a tenfold higher…
Education Five Questions about Magnesium 16 Nov 20239 Jul 2024 Influencers online are raving about the alleged effects of magnesium. They claim it makes you burst with energy and helps with various ailments, such as fatigue and brain fog. But…
Publications Oral magnesium supplementation does not affect insulin sensitivity in people with insulin-treated type 2 diabetes and a low serum magnesium: a randomised controlled trial 3 Nov 20239 Jul 2024 Drenthen LCA, de Baaij JHF, Rodwell L, van Herwaarden AE, Tack CJ, de Galan BE. Diabetologia. 2024 Jan;67(1):52-61 Abstract Aims/hypothesis: Hypomagnesaemia has been associated with insulin resistance and an increased risk of…
Publications Cleft palate and minor metabolic disturbances in a mouse global Arl15 gene knockout 1 Nov 20239 Jul 2024 Bai Y, Bentley L, Ma C, Naveenan N, Cleak J, Wu Y, Simon MM, Westerberg H, Cañas RC, Horner N, Pandey R, Paphiti K, Schulze U, Mianné J, Hough T,…
News Best Publication of 2022 Award 13 Oct 20239 Jul 2024 The Dutch Federation of Nephrology selected our paper on the identification of mtDNA mutations as cause of Gitelman syndroom as the Best Publication of 2022! Read more
Publications Electrolyte Disorders in Mitochondrial Cytopathies: A Systematic Review 5 Oct 20239 Jul 2024 Viering DHHM, Vermeltfoort L, Bindels RJM, Deinum J, de Baaij JHF. J Am Soc Nephrol. 2023 Nov 1;34(11):1875-1888. Abstract Background: Electrolyte reabsorption in the kidney has a high energy demand. Proximal and…