Publications Liver and spleen predominantly mediate calciprotein particle clearance in a rat model of chronic kidney disease 3 Apr 20249 Jul 2024 Zeper LW, Bos C, Leermakers PA, Franssen GM, Raavé R, Hoenderop JGJ, de Baaij JHF Am J Physiol Renal Physiol. 2024 Apr 1;326(4):F622-F634 Abstract Calciprotein particles (CPPs) provide an efficient mineral…
Publications Magnesium reabsorption in the kidney 17 Feb 20239 Jul 2024 de Baaij JHF Am J Physiol Renal Physiol. 2023 Mar 1;324(3):F227-F244. Abstract Mg2+ is essential for many cellular and physiological processes, including muscle contraction, neuronal activity, and metabolism. Consequently, the blood…
Publications Transcription factor HNF1β controls a transcriptional network regulating kidney cell structure and tight junction integrity 22 Dec 20229 Jan 2023 Mutations in the HNF1B gene cause autosomal dominant tubulointerstitial kidney disease (ADTKD)-HNF1β, a rare and heterogenous disease characterized by renal cysts and/or malformation, maturity-onset diabetes of the young, hypomagnesemia and…
Publications SLC41A1 knockout mice display normal magnesium homeostasis 19 Oct 20229 Jan 2023 Transcellular Mg2+ reabsorption in the distal convoluted tubule (DCT) of the kidneys plays an important role in maintaining systemic Mg2+ homeostasis. SLC41A1 is a Na+/Mg2+ exchanger that mediates Mg2+ efflux from cells and is…
Kidney Physiology 