Our mission is to decipher the pathophysiological mechanisms of magnesium disorders. By identification of genes involved in hereditary hypomagnesemia, we aim to increase our understanding of the molecular mechanisms of magnesium reabsorption in the kidney. Embedded in the department of Medical BioSceinces of Radboudumc, we study the regulation of magnesium…Continue reading “Magnesium in Health & Disease”
Kidney Physiology
Radboud university medical center, Nijmegen, The Netherlands
Publication highlights
Magnesium disorders
Touyz RM, de Baaij JHF, Hoenderop JGJ N Engl J Med. 2024 Jun 6;390(21):1998-2009. Abstract Although the past several years have…
Electrolyte Disorders in Mitochondrial Cytopathies: A Systematic Review
Viering DHHM, Vermeltfoort L, Bindels RJM, Deinum J, de Baaij JHF. J Am Soc Nephrol. 2023 Nov 1;34(11):1875-1888. Abstract Background: Electrolyte reabsorption…
Long-Read Sequencing Identifies Novel Pathogenic Intronic Variants in Gitelman Syndrome
Background – Gitelman syndrome is a salt-losing tubulopathy characterized by hypokalemic alkalosis and hypomagnesemia. It is caused by homozygous recessive or compound…
Kidney Physiology 