Jeroen de Baaij – Page 5 – Kidney Physiology

ARL15 modulates magnesium homeostasis through N-glycosylation of CNNMs

5 Jun 202110 Jan 2023

Cyclin M (CNNM1-4) proteins maintain cellular and body magnesium (Mg2+) homeostasis. Using various biochemical approaches, we have identified members of the CNNM family as direct interacting partners of ADP-ribosylation factor-like…

Genetic and drug-induced hypomagnesemia: different cause, same mechanism

21 Apr 202110 Jan 2023

Magnesium (Mg2+) plays an essential role in many biological processes. Mg2+ deficiency is therefore associated with a wide range of clinical effects including muscle cramps, fatigue, seizures and arrhythmias. To maintain…